Document Detail

Are AgNORs useful in distinguishing follicular hyperplasia from follicular lymphoma?
MedLine Citation:
PMID:  2693493     Owner:  NLM     Status:  MEDLINE    
Argyrophilic nucleolar organiser regions (AgNORs) in 28 follicular lymphomas and 30 lymph nodes showing reactive follicular hyperplasia were studied to see if they were helpful in distinguishing follicular lymphoma from follicular hyperplasia in paraffin wax tissue sections. Mean nuclear counts were greater in follicular hyperplasia (3.71 v 3.11). This difference was significant but counts overlapped so much that they were of no practical value in distinguishing between both conditions. Higher counts may reflect greater proliferative activity in follicular hyperplasia.
K Cronin; B M Loftus; P A Dervan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  42     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-03-09     Completed Date:  1990-03-09     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1267-8     Citation Subset:  AIM; IM    
Department of Pathology, Mater Misericordiae Hospital, Dublin, Eire.
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MeSH Terms
Giant Lymph Node Hyperplasia / diagnosis,  pathology*
Lymph Nodes / pathology
Lymphoma, Follicular / diagnosis,  pathology*
Nucleolus Organizer Region / pathology*
Comment In:
J Clin Pathol. 1990 Nov;43(11):964-5   [PMID:  2262576 ]

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