| Architecture of the thrombi removed from coronary artery bypass grafts in a patient with acute myocardial infarction. | |
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MedLine Citation:
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PMID: 20182769 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Using scanning electron microscopy we analyzed thrombotic material removed from coronary bypass grafts in a 57-year-old woman with multilevel atherosclerosis presenting with acute myocardial infarction (AMI). A white thrombotic material removed from the marginal branch bypass that contained large amounts of activated platelets displaying pseudopodia clearly visible at a higher magnification with a relatively low amount of fibrin. The other thrombus obtained from the right posterior descendent branch (RPD) bypass showed a highly organized fibrin structure composed of thicker fibers with low amounts of cellular components. Our findings indicate that the thrombus structure is different in AMI patients in whom the infarct-related vessel is vein anastomosis compared to those with a native coronary artery occluded. These findings help explain resistance of such thrombi to fibrinolysis and faster plaque growth related to fibrin accumulation. |
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Authors:
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Grzegorz Marek; Anna Kablak-Ziembicka; Ewa Stepien; Anetta Undas |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of thrombosis and thrombolysis Volume: 30 ISSN: 1573-742X ISO Abbreviation: J. Thromb. Thrombolysis Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-24 Completed Date: 2011-02-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9502018 Medline TA: J Thromb Thrombolysis Country: Netherlands |
Other Details:
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Languages: eng Pagination: 372-4 Citation Subset: IM |
Affiliation:
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Institute of Cardiology, Jagiellonian University School of Medicine, 80 Pradnicka Str, 31-202 Krakow, Poland. gmarek@poczta.onet.pl |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Atherosclerosis Cell Shape Coronary Artery Bypass / adverse effects* Female Fibrin / ultrastructure Humans Microscopy, Electron, Scanning Middle Aged Myocardial Infarction* Platelet Activation Pseudopodia Thrombosis / pathology* |
| Chemical | |
Reg. No./Substance:
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9001-31-4/Fibrin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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