| Archaebacterial bipolar tetraether lipids: Physico-chemical and membrane properties. | |
| | |
MedLine Citation:
|
PMID: 20060818 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Bipolar tetraether lipids (BTL) are abundant in archaea and can be chemically synthesized. The structures of BTL are distinctly different from the lipids found in bacteria and eukaryotes. In aqueous solution, BTL can form extraordinarily stable liposomes with different sizes, lamellarities and membrane packing densities. BTL liposomes can serve as membrane models for understanding the structure-function relationship of the plasma membrane in thermoacidophiles and can be used for technological applications. This article reviews the separation, characterization and structures of BTL as well as the physical properties and technological applications of BTL liposomes. One of the structural features of BTL is the presence of cyclopentane rings in the lipid hydrocarbon core. Archaea use the cyclopentane ring as an adaptation strategy to cope with high growth temperature. Special attention of this article is focused on how the number of cyclopentane rings varies with environmental factors and affects membrane properties. |
| | |
Authors:
|
Parkson Lee-Gau Chong |
Related Documents
:
|
14744478 - Liposomes and disaccharides as carriers in spray-dried powder formulations of superoxid... 6411718 - Interaction of the serum amyloid a proteins with phospholipid. 20055088 - Interaction of fullerenes c60 with large unilamellar vesicles. 15707728 - Investigation of liposomes as carriers of sodium ascorbyl phosphate for cutaneous photo... 6139428 - Extracellular excitatory junctional current at the crayfish neuromuscular junction. 7333288 - Visualization of the "membrane skeleton" in human erythrocytes by freeze-etching. |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review Date: 2010-01-12 |
Journal Detail:
|
Title: Chemistry and physics of lipids Volume: 163 ISSN: 1873-2941 ISO Abbreviation: Chem. Phys. Lipids Publication Date: 2010 Mar |
Date Detail:
|
Created Date: 2010-03-01 Completed Date: 2010-06-01 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0067206 Medline TA: Chem Phys Lipids Country: Ireland |
Other Details:
|
Languages: eng Pagination: 253-65 Citation Subset: IM |
Copyright Information:
|
Copyright 2010 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
|
Department of Biochemistry, Temple University School of Medicine, Philadelphia, PA 19140, United States. pchong02@temple.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Archaea
/
chemistry* Cell Membrane / chemistry* Lipids / chemistry* Magnetic Resonance Spectroscopy Mass Spectrometry Molecular Structure |
| Chemical | |
Reg. No./Substance:
|
0/Lipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Characterization of a high-activity mutant of human butyrylcholinesterase against (-)-cocaine.
Next Document: Cationic lipid-mediated nucleic acid delivery: beyond being cationic.