Document Detail


Arabidopsis mutants deregulated in RCI2A expression reveal new signaling pathways in abiotic stress responses.
MedLine Citation:
PMID:  15860016     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To uncover new pathways involved in low-temperature signal transduction, we screened for mutants altered in cold-induced expression of RCI2A, an Arabidopsis gene that is not a member of the CBF/DREB1 regulon and is induced not only by low temperature but also by abscisic acid (ABA), dehydration (DH) and NaCl. This was accomplished by generating a line of Arabidopsis carrying a transgene consisting of the RCI2A promoter fused to the firefly luciferase coding sequence. A number of mutants showing low or high RCI2A expression in response to low temperature were identified. These mutants also displayed deregulated RCI2A expression in response to ABA, DH or NaCl. Interestingly, however, they were not altered in stress-induced expression of RD29A, a CBF/DREB1-target gene, suggesting that the mutations affect signaling intermediates of CBF/DREB1-independent regulatory pathways. Several mutants showed alterations in their tolerance to freezing, DH or salt stress, as well as in their ABA sensitivity, which indicates that the signaling intermediates defined by the corresponding mutations play an important role in Arabidopsis tolerance to abiotic stresses. Based on the mutants identified, we discuss the involvement of CBF/DREB1-independent pathways in modulating stress signaling.
Authors:
Joaquín Medina; Marta Rodríguez-Franco; Andrés Peñalosa; María J Carrascosa; Gunther Neuhaus; Julio Salinas
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Plant journal : for cell and molecular biology     Volume:  42     ISSN:  0960-7412     ISO Abbreviation:  Plant J.     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-04-29     Completed Date:  2005-08-11     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9207397     Medline TA:  Plant J     Country:  England    
Other Details:
Languages:  eng     Pagination:  586-97     Citation Subset:  IM    
Affiliation:
Departamento de Biotecnología, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Carretera de la Coruña, Km. 7, 28040 Madrid, Spain.
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MeSH Terms
Descriptor/Qualifier:
Abscisic Acid / physiology
Arabidopsis / genetics,  metabolism*
Arabidopsis Proteins / genetics,  metabolism*
Cold Temperature
Gene Expression Regulation, Plant / physiology*
Heat-Shock Proteins / genetics,  metabolism*
Membrane Proteins / genetics,  metabolism*
Mutation
Phenotype
Plants, Genetically Modified
Signal Transduction / physiology*
Sodium Chloride
Water / metabolism
Chemical
Reg. No./Substance:
0/Arabidopsis Proteins; 0/Heat-Shock Proteins; 0/Membrane Proteins; 0/RCI2A protein, Arabidopsis; 21293-29-8/Abscisic Acid; 7647-14-5/Sodium Chloride; 7732-18-5/Water

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