Document Detail


Aquatic exercise improves the monocyte pro- and anti-inflammatory cytokine production balance in fibromyalgia patients.
MedLine Citation:
PMID:  20536907     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Current hypotheses of the etiology of fibromyalgia (FM) include inflammatory disorders. We evaluated the effect of a pool-aquatic exercise program (8 months, two weekly 60-min sessions) on the inflammatory cytokine production by isolated monocytes, and on the serum concentration of C-reactive protein (CRP), in a group of female FM patients. Monocytes from FM patients released more IL-1β, TNFα, IL-6, and IL-10 than those from an age-matched control group of healthy women (HW). This inflammatory disorder in FM women was also manifested by high circulating concentrations of CRP. Increased IL-6 with a concomitant decreased TNFα spontaneous release was found after 4 months (midway through) of the exercise program. At the end of the program (8 months), monocytes from FM patients showed diminished spontaneous production of pro-/anti-inflammatory cytokines, with a similar spontaneous release of IL-1β and IL-6 to that of HW, but a lower production of TNFα and higher of IL-10. Lipopolysaccharide-induced production of IL-1β, TNFα, IL-6, and IL-10 also decreased at the end of the exercise program, although IL-10 remained higher than HW. The anti-inflammatory effect of the exercise program was also corroborated by a decrease in the circulating CRP concentration. Exercise also improved the health-related quality of life of FM patients.
Authors:
E Ortega; M E Bote; E Giraldo; J J García
Related Documents :
19339927 - Exercise effects in patients with adult idiopathic inflammatory myopathies.
22701757 - Oxidants, antioxidants, and the beneficial roles of exercise-induced production of reac...
15948087 - Validity of pedometers for measuring exercise adherence in heart failure patients.
17560347 - Information and uncertainty in remote perception research.
16541377 - Effects of prior exercise on force-velocity test performance and quadriceps emg.
14747227 - Cardiac abnormalities in diabetic patients with neuropathy: effects of aldose reductase...
Publication Detail:
Type:  Journal Article     Date:  2010-06-01
Journal Detail:
Title:  Scandinavian journal of medicine & science in sports     Volume:  22     ISSN:  1600-0838     ISO Abbreviation:  Scand J Med Sci Sports     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111504     Medline TA:  Scand J Med Sci Sports     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  104-12     Citation Subset:  IM    
Copyright Information:
© 2010 John Wiley & Sons A/S.
Affiliation:
Research Group in Immunophysiology: Exercise, Stress and Health, Department of Physiology, Faculty of Sciences, University of Extremadura, Badajoz, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Impaired semantic processing during task-set switching: Evidence from the N400 in rapid serial visua...
Next Document:  Single nucleotide polymorphisms in the myostatin (MSTN) and muscle creatine kinase (CKM) genes are n...