Document Detail


Aprotinin in the management of coagulopathy associated with amniotic fluid embolus.
MedLine Citation:
PMID:  16715609     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Amniotic fluid embolus, also known as anaphylactoid syndrome of pregnancy is a rare complication of pregnancy. When it occurs, the maternal mortality rate may be as high as 86%, and in survivors, the morbidity rate may be just as high. Hallmark clinical features include maternal cardiovascular collapse with disseminated intravascular coagulation, and fetal distress. Management centers on strategies to improve oxygenation, support circulation, and correct the coagulopathy. We report the case of a patient who developed amniotic fluid embolus and was effectively managed with aprotinin to control the coagulopathy associated with this devastating complication of pregnancy.
Authors:
Jeffrey Stroup; Davin Haraway; J Martin Beal
Related Documents :
3621059 - The role of fetal urinary excretion in the transfer of ethanol into amniotic fluid afte...
2277279 - Polyhydramnios and perinatal outcome.
2654909 - Intrauterine manometry: technique and application to fetal pathology.
22384419 - Comparison of elective single cleavage-embryo transfer to elective single blastocyst-em...
3601279 - A microbiologic and clinical study of placental inflammation at term.
8950859 - Persistent foetal tachycardia as an early marker of chorion-amnionitis. description of ...
7305759 - Progesterone control of the initiation of lactose synthesis in the rat.
21974929 - Fetal progenitor cells naturally transferred through pregnancy participate in inflammat...
7889589 - Epidural analgesia for labour in a patient with ebstein's anomaly.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pharmacotherapy     Volume:  26     ISSN:  0277-0008     ISO Abbreviation:  Pharmacotherapy     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-05-22     Completed Date:  2006-09-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8111305     Medline TA:  Pharmacotherapy     Country:  United States    
Other Details:
Languages:  eng     Pagination:  689-93     Citation Subset:  IM    
Affiliation:
University of Oklahoma College of Pharamcy, Tulsa, 74135, USA. Jeffrey-Stroup@ouhsc.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aprotinin / therapeutic use*
Blood Cell Count
Blood Coagulation Disorders / drug therapy*,  etiology*
Blood Coagulation Tests
Embolism, Amniotic Fluid / physiopathology*
Female
Hemostatics / therapeutic use*
Humans
Isotonic Solutions / therapeutic use
Plasma Substitutes / therapeutic use
Pregnancy
Uterus / physiopathology
Chemical
Reg. No./Substance:
0/Hemostatics; 0/Isotonic Solutions; 0/Plasma Substitutes; 0/crystalloid solutions; 9087-70-1/Aprotinin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cytomegalovirus infection in lung transplant patients: the role of prophylaxis and recipient-donor s...
Next Document:  Pharmacokinetics of daptomycin in a critically ill adolescent with vancomycin-resistant enterococcal...