Document Detail

Approaches to the initial respiratory management of preterm neonates.
MedLine Citation:
PMID:  12615026     Owner:  NLM     Status:  MEDLINE    
Newly born preterm infants often require respiratory support. Various approaches have been taken to provide this support, including elective intubation and ventilation, prophylactic surfactant and continuous positive airway pressure (CPAP). Elective intubation and ventilation allow the clinician to take control of the baby's airway and reduce the support as tolerated. Surfactant can be administered prophylactically to prevent lung injury and respiratory complications. Many neonatologists, however, advocate a less aggressive approach to the provision of support, which includes the application of early nasal CPAP with intubation and ventilation only if necessary. Avoiding intubation may be effective in minimising ventilator-induced lung injury, but withholding surfactant may be detrimental to the infant. In this paper, we examine the advantages and disadvantages of the different approaches that can be taken in providing respiratory support to preterm neonates shortly after birth and examine some strategies that integrate them.
Michael S Dunn; Maureen Charlotte Reilly
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Paediatric respiratory reviews     Volume:  4     ISSN:  1526-0542     ISO Abbreviation:  Paediatr Respir Rev     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-03-04     Completed Date:  2003-08-05     Revised Date:  2009-10-14    
Medline Journal Info:
Nlm Unique ID:  100898941     Medline TA:  Paediatr Respir Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  2-8     Citation Subset:  IM    
Copyright Information:
Copyright 2003 Elsevier Science Ltd.
Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada.
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MeSH Terms
Infant, Newborn
Infant, Premature*
Intubation, Intratracheal
Positive-Pressure Respiration / methods*
Pulmonary Surfactants / therapeutic use*
Respiration, Artificial* / adverse effects
Respiratory Distress Syndrome, Newborn / therapy*
Reg. No./Substance:
0/Pulmonary Surfactants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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