Document Detail


Approach to the diagnosis and management of tuberculous meningitis.
MedLine Citation:
PMID:  21308544     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Meningitis caused by Mycobacterium tuberculosis remains an important cause of morbidity and mortality worldwide, and presents particular challenges in terms of diagnosis and management. The nonspecific clinical presentation of tuberculous meningitis (TBM) has led researchers to develop newer molecular methods of making the diagnosis. Several of these methods have excellent sensitivity and specificity, although many are not yet available for clinical use. Successful treatment of TBM requires a combination of antimicrobial agents, with vigilance regarding the possibility of disease caused by resistant organisms. Adjunctive corticosteroids also have a role in treating this potentially devastating infection, as can neurosurgery. With proper therapy, morbidity and mortality can be minimized in patients with TBM.
Authors:
Scott W Sinner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current infectious disease reports     Volume:  12     ISSN:  1534-3146     ISO Abbreviation:  Curr Infect Dis Rep     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2011-02-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888983     Medline TA:  Curr Infect Dis Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  291-8     Citation Subset:  -    
Affiliation:
Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ, USA, scottsinner@hotmail.com.
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