Document Detail


Approach and management of primary ectopic breast carcinoma in the axilla: where are we? A comprehensive historical literature review.
MedLine Citation:
PMID:  20934398     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Primary ectopic breast carcinoma is a rare disease and, at present, no specific guidelines on its diagnosis and treatment are available. The purpose of this article is to review the world literature in English on primary ectopic breast carcinoma located in the armpit and to offer guidelines for diagnosis and treatment. Data for this review were identified by searches of MEDLINE, PubMed, The Cochrane Library, ACNP (Italian catalogue of journals) and references from relevant articles using relevant search terms and data published in the previous reviews. Primary ectopic breast carcinoma of the axilla mostly affects women of over 40 (range 28-90 yrs) years of age. The most frequent histological diagnosis is invasive ductal carcinoma not otherwise specified (NOS) (72%). Because of its rareness, in most cases, the diagnosis is delayed for on average 40.5 months. This disease is rare, but a high level of suspicion for carcinoma is mandatory when confronted with a tumour in this area. Once diagnosed, patients should undergo staging, and prognostic and adjuvant treatment procedures identical to orthotopic breast carcinoma guidelines. There are some limitations for the staging. Loco-regional treatment, on indication, combined with endocrine therapy and/or chemotherapy seems the treatment of choice.
Authors:
Giuseppe Visconti; Yassir Eltahir; Robert J Van Ginkel; Joost Bart; Paul M N Werker
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-10-12
Journal Detail:
Title:  Journal of plastic, reconstructive & aesthetic surgery : JPRAS     Volume:  64     ISSN:  1878-0539     ISO Abbreviation:  J Plast Reconstr Aesthet Surg     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-20     Completed Date:  2011-01-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101264239     Medline TA:  J Plast Reconstr Aesthet Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  e1-11     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Department of Plastic and Reconstructive Surgery, Catholic University of Sacro Cuore-University Hospital A. Gemelli, Largo A. Gemelli 8, 00168 Rome, Italy. joevisconti@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Axilla*
Biopsy, Needle
Breast*
Breast Neoplasms / mortality,  pathology*,  therapy
Carcinoma, Ductal, Breast / mortality,  pathology*,  therapy
Chemotherapy, Adjuvant
Choristoma / diagnosis*
Combined Modality Therapy
Female
Follow-Up Studies
Humans
Immunohistochemistry
Italy
Mastectomy, Segmental / methods
Neoplasm Staging
Radiotherapy, Adjuvant
Rare Diseases
Risk Assessment
Survival Analysis
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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