Document Detail

Appraisal of sinus node artery disease.
MedLine Citation:
PMID:  1149209     Owner:  NLM     Status:  MEDLINE    
The relationship of depressed sinus node function to coronary artery disease (CAD) was evaluated. The sinus node artery (SNA) was easily identified in all of 80 unselected normal coronary arteriograms. Angiographic disease of, or significant obstruction proximal to, the SNA was seen in 21% of 80 unselected CAD patients. Heart rate and sinoatrial recovery times (SART) were obtained in 50 consecutive unmedicated patients prior to arteriography. There was no difference between the SART of 23 CAD patients free of SNA involvement (1092 msec +/- 55 sem) and 18 normals (1070 +/- 40 msec). Nine patients with SNA involvement had shorter SART (941 +/- 52 MSEC) than normals (P less than 0.05) or other CAD patients (NS). Similar results were obtained for heart rate. No patient with SNA involvement had a prolonged SART or sick sinus syndrom (SSS). six of the 50 patients studied were symptomatic with SSS. Five of these SSS patients had CAD but none had angiographic evidence of SNA involvement. Obstructions involving the SNA were common in CAD but were not associated with altered heart rate or SART. Patients with SSS exhibited no angiographic evidence of SNA involvement. Therefore, it is unlikely that SSS is related to CAD of the SNA.
T R Engel; S G Meister; G S Feitosa; H A Fischer; W S Frankl
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Circulation     Volume:  52     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1975 Aug 
Date Detail:
Created Date:  1975-11-08     Completed Date:  1975-11-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  286-91     Citation Subset:  AIM; IM    
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MeSH Terms
Arrhythmia, Sinus / diagnosis,  etiology*,  physiopathology
Coronary Angiography
Coronary Disease / complications*,  diagnosis,  physiopathology
Heart Block / diagnosis
Heart Catheterization
Heart Rate
Middle Aged
Pacemaker, Artificial
Sinoatrial Block / etiology,  physiopathology
Sinoatrial Node / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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