| Applications of arterial spin labeled MRI in the brain. | |
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MedLine Citation:
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PMID: 22246782 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Perfusion provides oxygen and nutrients to tissues and is closely tied to tissue function while disorders of perfusion are major sources of medical morbidity and mortality. It has been almost two decades since the use of arterial spin labeling (ASL) for noninvasive perfusion imaging was first reported. While initial ASL magnetic resonance imaging (MRI) studies focused primarily on technological development and validation, a number of robust ASL implementations have emerged, and ASL MRI is now also available commercially on several platforms. As a result, basic science and clinical applications of ASL MRI have begun to proliferate. Although ASL MRI can be carried out in any organ, most studies to date have focused on the brain. This review covers selected research and clinical applications of ASL MRI in the brain to illustrate its potential in both neuroscience research and clinical care. J. Magn. Reson. Imaging 2012;. © 2012 Wiley Periodicals, Inc. |
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Authors:
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John A Detre; Hengyi Rao; Danny J J Wang; Yu Fen Chen; Ze Wang |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-13 |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: - ISSN: 1522-2586 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Wiley Periodicals, Inc. |
Affiliation:
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Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Center for Functional Neuroimaging, University of Pennsylvania, Philadelphia, Pennsylvania, USA. detre@mail.med.upenn.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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