Document Detail

Applications of ambulatory blood pressure monitoring in clinical practice.
MedLine Citation:
PMID:  1914204     Owner:  NLM     Status:  MEDLINE    
Traditionally, blood pressure has been measured by the sphygmomanometer in the medical office. There is growing evidence, however, that office blood pressures may not be typical of values throughout the day. Between 20% and 30% of patients diagnosed with hypertension in the office actually are normotensive at other times. Ambulatory blood pressure monitoring with small, portable devices that automatically measure blood pressure every few minutes throughout the day appears to be an appropriate tool when "white-coat" hypertension is suspected--i.e., for individuals whose hypertension in the physician's office is not associated with other physical or historical evidence for cardiovascular disease or with other risk factors. Used prudently, ambulatory monitoring is a cost-effective technique that potentially can prevent unnecessary treatment of patients. Moreover, whole-day measurements may correlate more closely than office measurements may correlate more closely than office measurements do with findings of cardiovascular disease. This new approach also has highlighted the circadian pattern of blood pressure, especially the sharp early to mid-morning increase that coincides with an increased tendency to major cardiovascular events. This has focused attention on directing antihypertensive therapy towards the morning hours. Ambulatory monitoring is now used routinely in studies of antihypertensive drugs. This technique has no placebo effect and takes fewer patients to assess drug efficacy than do conventional methods.
M A Weber; D H Smith; J M Neutel; D G Cheung
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical chemistry     Volume:  37     ISSN:  0009-9147     ISO Abbreviation:  Clin. Chem.     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1991-11-20     Completed Date:  1991-11-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9421549     Medline TA:  Clin Chem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1880-4     Citation Subset:  IM    
Hypertension Center, Veterans Affairs Medical Center, Long Beach, CA 90822.
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MeSH Terms
Antihypertensive Agents / therapeutic use
Blood Pressure Monitors
Circadian Rhythm
Electrocardiography, Ambulatory
Hypertension / diagnosis*,  drug therapy
Reg. No./Substance:
0/Antihypertensive Agents

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