| Applications of 'TissueQuant'- A color intensity quantification tool for medical research. | |
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MedLine Citation:
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PMID: 21924792 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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This paper demonstrates the use of TissueQuant - an image analysis tool for quantification of color intensities which was developed for use in medical research where the stained biological specimen such as tissue or antigen needs to be quantified. TissueQuant provides facilities for user interaction to choose and quantify the color of interest and its shades. Gaussian weighting functions are used to provide a color score which quantifies how close the shade is to the user specified reference color. We describe two studies in medical research which use TissueQuant for quantification. The first study evaluated the effect of petroleum-ether extract of Cissus quadrangularis (CQ) on osteoporotic rats. It was found that the analysis results correlated well with the manual evaluation, p<0.001. The second study evaluated the nerve morphometry and it was found that the adipose and non adipose tissue content was maximum in radial nerve among the five nerves studied. |
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Authors:
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Keerthana Prasad; Bhagath Kumar P; Marx Chakravarthy; Gopalakrishna Prabhu |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-15 |
Journal Detail:
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Title: Computer methods and programs in biomedicine Volume: - ISSN: 1872-7565 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8506513 Medline TA: Comput Methods Programs Biomed Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Manipal Centre for Information Science, Manipal University, Manipal 576104, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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