Document Detail


Applications and Potential Toxicity of Magnetic Iron Oxide Nanoparticles.
MedLine Citation:
PMID:  23019129     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Owing to their unique physical and chemical properties, magnetic iron oxide nanoparticles have become a powerful platform in many diverse aspects of biomedicine, including magnetic resonance imaging, drug and gene delivery, biological sensing, and hyperthermia. However, the biomedical applications of magnetic iron oxide nanoparticles arouse serious concerns about their pharmacokinetics, metabolism, and toxicity. In this review, the updated research on the biomedical applications and potential toxicity of magnetic iron oxide nanoparticles is summarized. Much more effort is required to develop magnetic iron oxide nanoparticles with improved biocompatible surface engineering to achieve minimal toxicity, for various applications in biomedicine.
Authors:
Gang Liu; Jinhao Gao; Hua Ai; Xiaoyuan Chen
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-28
Journal Detail:
Title:  Small (Weinheim an der Bergstrasse, Germany)     Volume:  -     ISSN:  1613-6829     ISO Abbreviation:  Small     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101235338     Medline TA:  Small     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Affiliation:
Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361005 China; Sichuan Key Laboratory of Medical Imaging, North Sichuan Medical College, Nanchong, 637007, China. gangliu.cmitm@xmu.edu.cn.
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