Document Detail


Application of terahertz spectroscopy to the characterization of biological samples using birefringence silicon grating.
MedLine Citation:
PMID:  22734784     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We present a device and method for performing vector transmission spectroscopy on biological specimens at terahertz (THz) frequencies. The device consists of artificial dielectric birefringence obtained from silicon microfluidic grating structures. The device can measure the complex dielectric function of a liquid, across a wide THz band of 2 to 5.5 THz, using a Fourier transform infrared spectrometer. Measurement data from a range of liquid specimens, including sucrose, salmon deoxyribonucleic acid (DNA), herring DNA, and bovine serum albumin protein solution in water are presented. The specimen handling is simple, using a microfluidic channel. The transmission through the device is improved significantly and thus the measurement accuracy and bandwidth are increased.
Authors:
Shimul C Saha; James P Grant; Yong Ma; Ata Khalid; Feng Hong; David R S Cumming
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of biomedical optics     Volume:  17     ISSN:  1560-2281     ISO Abbreviation:  J Biomed Opt     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9605853     Medline TA:  J Biomed Opt     Country:  United States    
Other Details:
Languages:  eng     Pagination:  067006     Citation Subset:  IM    
Affiliation:
University of Glasgow, Electronics and Nanoscale Engineering, Rankine Building, G12 8LT, United Kingdom.
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