Document Detail

Application of pyramided traits against Lepidoptera in insect resistance management for Bt crops.
MedLine Citation:
PMID:  22688687     Owner:  NLM     Status:  MEDLINE    
Since initial launch of insect protected transgenic crops, the most effective strategy to manage the potential for target pests to evolve resistance has been the use of a single mode of action with "high dose" and structured refuge. However, the effectiveness of this strategy is limited if mortality of certain pests does not reach "high dose" criteria, inconsistent implementation of refuges and non-rare resistance alleles. More recently, several pyramided trait products, which include multiple modes of action against key target pests, have been developed. These products offer the potential for dramatically improved resistance management with smaller refuges and less dependence on high mortality of susceptible and heterozygous insects and rare resistance alleles. We show that products such as SmartStax and PowerCore offer compelling resistance management benefits compared with single mode of action products and allow for the option of products containing refuge seed mixtures rather than structured refuges to effectively delay resistance. We conclude that all stakeholders, including technology developers, growers, crop advisors, extensions services and regulatory authorities should continue to encourage the development, deployment and adoption of pyramided trait products for improved pest management and improved resistance management.
Nicholas P Storer; Gary D Thompson; Graham P Head
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Publication Detail:
Type:  Journal Article; Review     Date:  2012-07-01
Journal Detail:
Title:  GM crops & food     Volume:  3     ISSN:  2164-5701     ISO Abbreviation:  GM Crops Food     Publication Date:    2012 Jul-Sep
Date Detail:
Created Date:  2012-08-22     Completed Date:  2014-08-25     Revised Date:  2014-10-09    
Medline Journal Info:
Nlm Unique ID:  101572655     Medline TA:  GM Crops Food     Country:  United States    
Other Details:
Languages:  eng     Pagination:  154-62     Citation Subset:  IM    
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MeSH Terms
Bacillus thuringiensis / genetics*
Bacterial Proteins / genetics
Bacterial Toxins / genetics
Crops, Agricultural / genetics*
Insecticide Resistance*
Lepidoptera / physiology*
Pest Control, Biological*
Plants, Genetically Modified*
Reg. No./Substance:
0/Bacterial Proteins; 0/Bacterial Toxins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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