| Application of prebiotics in infant foods. | |
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MedLine Citation:
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PMID: 15877896 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The rationale for supplementing an infant formula with prebiotics is to obtain a bifidogenic effect and the implied advantages of a 'breast-fed-like' flora. So far, the bifidogenic effect of oligofructose and inulin has been demonstrated in animals and in adults, of oligofructose in infants and toddlers and of a long-chain inulin (10 %) and galactooligosaccharide (90 %) mixture in term and preterm infants. The addition of prebiotics to infant formula softens stools but other putative effects remain to be demonstrated. Studies published post marketing show that infants fed a long-chain inulin/galactooligosaccharide mixture (0.8 g/dl) in formula grow normally and have no side-effects. The addition of the same mixture at a concentration of 0.8 g/dl to infant formula was therefore recognized as safe by the European Commission in 2001 but follow-up studies were recommended. It is thought that a bifidogenic effect is beneficial for the infant host. The rising incidence in allergy during the first year of life may justify the attempts to modulate the infant's flora. Comfort issues should not be confused with morbidity and are likely to be multifactorial. The functional effects of prebiotics on infant health need further study in controlled intervention trials. |
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Authors:
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Gigi Veereman-Wauters |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The British journal of nutrition Volume: 93 Suppl 1 ISSN: 0007-1145 ISO Abbreviation: Br. J. Nutr. Publication Date: 2005 Apr |
Date Detail:
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Created Date: 2005-05-09 Completed Date: 2005-08-08 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372547 Medline TA: Br J Nutr Country: England |
Other Details:
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Languages: eng Pagination: S57-60 Citation Subset: IM |
Affiliation:
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Queen Paola Children's Hospital, ZNA, Antwerp, Belgium. gveereman@skynet.be |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bifidobacterium Breast Feeding Dietary Fiber / administration & dosage* Humans Infant Infant Food* Infant, Newborn Infant, Premature Intestinal Mucosa / immunology, microbiology Inulin / administration & dosage* Lactobacillus Oligosaccharides / administration & dosage* Probiotics / administration & dosage Randomized Controlled Trials as Topic Weaning |
| Chemical | |
Reg. No./Substance:
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0/Oligosaccharides; 0/oligofructose; 9005-80-5/Inulin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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