Document Detail

Application of a numerical index of discriminatory power to a comparison of four physiochemical typing methods for Candida albicans.
MedLine Citation:
PMID:  2685017     Owner:  NLM     Status:  MEDLINE    
Four typing methods for the strain differentiation of Candida albicans (morphotyping, resistotyping, extracellular enzyme production, and carbon source assimilation reactions) were compared on a single population of 100 strains. An index of discriminatory power was used to facilitate this comparison. Extracellular enzyme production had poor discriminatory power, and carbon source assimilation reactions were poorly reproducible. Morphotyping and resistotyping had acceptable reproducibility and discrimination. The use of resistotyping and morphotyping in parallel enhanced discrimination without an unacceptable decrease in reproducibility, although other combinations did not enhance discrimination because reproductibility was impaired.
P R Hunter; C A Fraser
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of clinical microbiology     Volume:  27     ISSN:  0095-1137     ISO Abbreviation:  J. Clin. Microbiol.     Publication Date:  1989 Oct 
Date Detail:
Created Date:  1990-01-09     Completed Date:  1990-01-09     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7505564     Medline TA:  J Clin Microbiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2156-60     Citation Subset:  IM    
Division of Hospital Infection, Central Public Health Laboratory, London, England.
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MeSH Terms
Candida albicans / classification*,  metabolism,  ultrastructure
Carbon / metabolism
Discriminant Analysis
Drug Resistance, Microbial
Enzymes / biosynthesis
Evaluation Studies as Topic
Reg. No./Substance:
0/Enzymes; 7440-44-0/Carbon

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