| Application of the moving-actuator type pump as a ventricular assist device: in vitro and in vivo studies. | |
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MedLine Citation:
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PMID: 12117296 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A moving actuator type pump has been developed as a multifunctional Korean artificial heart (AnyHeart). The pump consists of a moving actuator as an energy converter, right and left sacs, polymer (or mechanical) valves, and a rigid polyurethane housing. The actuator containing a brushless DC motor moves back and forth on an epicyclical gear train to produce a pendular motion, which compresses both sacs alternately. Of its versatile functions of ventricular assist device and total artificial heart use, we have evaluated the system performance as a single or biventricular assist device through in vitro and in vivo experiments. Pump performance and anatomical feasibility were tested using various animals of different sizes. In the case of single ventricular assist device (VAD) use, one of the sacs remained empty and a mini-compliance chamber was attached to either an outflow or inflow port of the unused sac. The in vitro and in vivo studies show acceptable performance and pump behavior. Further extensive study is required to proceed to human application. |
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Authors:
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H S Lee; Y R Rho; C Y Park; C M Hwang; W G Kim; K Sun; M J Choi; K K Lee; J T Cheong; E B Shim; B G Min |
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Publication Detail:
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Type: In Vitro; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The International journal of artificial organs Volume: 25 ISSN: 0391-3988 ISO Abbreviation: Int J Artif Organs Publication Date: 2002 Jun |
Date Detail:
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Created Date: 2002-07-15 Completed Date: 2003-01-03 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7802649 Medline TA: Int J Artif Organs Country: Italy |
Other Details:
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Languages: eng Pagination: 556-61 Citation Subset: IM |
Affiliation:
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Biomedical Engineering Department, College of Engineering, Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cattle Coronary Circulation / physiology Disease Models, Animal Equipment Design Feasibility Studies Goats Heart Failure / physiopathology, radiography, therapy* Heart-Assist Devices* Horses Humans Reproducibility of Results Sheep |
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