| [Application of molecular autopsy in sudden death caused by inherited arrhythmia]. | |
| | |
MedLine Citation:
|
PMID: 23213788 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
Sudden cardiac death (SCD) refers to sudden stop of breath and heartbeat and death within one hour caused by underlying cardiac diseases. Clinical manifestation of inherited arrhythmia is lethal arrhythmia without gross cardiac lesions, which can lead to SCD. The autopsy and pathological examination are difficult to identify the cause of death. Fatal mechanism of inherited arrhythmia is the change in the genes encoding for cardiac ion channel protein, which causes the dysfunctions of cardiac electrical activity. It is very important to detect genetic mutation by the technique of molecular biology in negative autopsy. This review presents the latest research on the relation between SCD and inherited arrhythmia, and the application of molecular autopsy used in identifying SCD due to inherited arrhythmia and its candidate gene. |
| | |
Authors:
|
Ye-hui Lü; Wen-can Li; Long Chen |
Publication Detail:
|
Type: English Abstract; Journal Article |
Journal Detail:
|
Title: Fa yi xue za zhi Volume: 28 ISSN: 1004-5619 ISO Abbreviation: Fa Yi Xue Za Zhi Publication Date: 2012 Oct |
Date Detail:
|
Created Date: 2012-12-06 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9426151 Medline TA: Fa Yi Xue Za Zhi Country: China |
Other Details:
|
Languages: chi Pagination: 362-5, 370 Citation Subset: IM |
Affiliation:
|
Department of Forensic Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China. 11211010058@fudan.edu.cn |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: [A new method of identifying the peripheral blood and the menstrual blood].
Next Document: [Progress on epigenetics applications in forensic science].