Document Detail


Application of magnetic resonance tractography in the perioperative planning of patients with eloquent region intra-axial brain lesions.
MedLine Citation:
PMID:  21371893     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We aimed to assess the role of preoperative diffusion tensor tractography (DTT) in the surgical planning and prognostication of the postoperative outcome of patients with lesions in the eloquent areas of the brain. From 2006 to 2009, 50 patients were preoperatively evaluated with DTT and image-guidance studies. Three-dimensional (3D) color trajectory maps of white-matter tracts adjacent to the lesions were reconstructed. The usefulness of tractography in perioperative planning was graded on a scale of 1 to 4. The postoperative outcomes were studied in relation to the pattern of tract involvement. The lesions included brain tumors in 40 patients, vascular malformations in five patients and other lesions in five patients. An awake craniotomy was performed in 19 patients. The tracts were only displaced in 72% of patients, completely infiltrated in 14% and had a combined pattern in 14%. DTT significantly altered the planning (score ⩾3) in 62% of patients. Patients with pure displacement had the best outcome, while those with infiltration had a poorer outcome. We conclude that tractography improves surgical safety and aids prognostication in surgery of patients with eloquent cortex lesions.
Authors:
Anshul Bagadia; Harshad Purandare; Basant K Misra; Santosh Gupta
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-1
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  -     ISSN:  1532-2653     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Neurosurgery and Gamma Knife Radiosurgery, PD Hinduja National Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim, Mumbai 400016, India.
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