| Application of immunohistochemistry to the isolated mucosa of the mouse gastrointestinal tract, with special reference to somatostatin cells. | |
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MedLine Citation:
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PMID: 2906495 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the present study, in order to easily grasp whole images of somatostatin (D) cells, the isolated mucosa of the mouse gastrointestinal tract was immunohistochemically treated. The present study revealed that: (1) in the stomach, small-intestinal villi and colon, about 20% of the D cells extrude basal cytoplasmic processes, showing terminal expansions in many cases; on the other hand, in the crypts of the small intestine, few D cells possess basal processes, and (2) in the stomach, there is no determined tendency in the direction of the basal processes of the D cells; on the other hand, in the small-intestinal villi and colon, most D cell basal processes run toward the villus base and colon crypt bottoms. The direction of the basal processes of the D cells in the gastrointestinal tract seems to be mostly in favor of the migration pattern of epithelial cells described previously. It is likely that, if the targets of the D cells are near the D cells, the basal process is not necessary for local secretion of somatostatin. During migration, however, D cells might extrude basal processes to keep relationships with their targets. |
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Authors:
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Y Satoh; Y Oomori; K Ishikawa; T Satoh; K Ono |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta anatomica Volume: 133 ISSN: 0001-5180 ISO Abbreviation: Acta Anat (Basel) Publication Date: 1988 |
Date Detail:
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Created Date: 1989-03-30 Completed Date: 1989-03-30 Revised Date: 2007-07-02 |
Medline Journal Info:
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Nlm Unique ID: 0370272 Medline TA: Acta Anat (Basel) Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 229-33 Citation Subset: IM |
Affiliation:
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Department of Anatomy, Asahikawa Medical College, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Digestive System / analysis, cytology*, metabolism Immunohistochemistry Male Mice Mice, Inbred ICR Mucous Membrane / analysis, cytology, metabolism Somatostatin / analysis, metabolism* |
| Chemical | |
Reg. No./Substance:
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51110-01-1/Somatostatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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