Document Detail


Application of hydroalcoholic solutions of formaldehyde in preparation of acetylsalicylic acid gastro-resistant capsules.
MedLine Citation:
PMID:  12056537     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Enteric coating of hard gelatin capsules by application of hydroalcoholic solutions of formaldehyde was studied and developed in accordance with previous publications. It is possible to affirm that this coating constitutes a simple, stable, reproducible, and inexpensive method, being a valid alternative to those which have been proposed. The aim of the present investigation is the preparation of acetylsalicylic acid gelatin capsules with good conditions of gastro-resistance and enteros solubility.
Authors:
M E Pina; A T Sousa
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Drug development and industrial pharmacy     Volume:  28     ISSN:  0363-9045     ISO Abbreviation:  Drug Dev Ind Pharm     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-06-11     Completed Date:  2002-11-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7802620     Medline TA:  Drug Dev Ind Pharm     Country:  United States    
Other Details:
Languages:  eng     Pagination:  443-9     Citation Subset:  IM    
Affiliation:
Laboratory of Galenic and Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra, Portugal.
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MeSH Terms
Descriptor/Qualifier:
Anti-Inflammatory Agents, Non-Steroidal / chemistry*
Aspirin / chemistry*
Capsules
Chemistry, Pharmaceutical
Cross-Linking Reagents / chemistry
Drug Stability
Ethanol
Excipients / chemistry
Fixatives / chemistry*
Formaldehyde / chemistry*
Gelatin / chemistry
Solubility
Solvents
Tablets, Enteric-Coated
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Capsules; 0/Cross-Linking Reagents; 0/Excipients; 0/Fixatives; 0/Solvents; 0/Tablets, Enteric-Coated; 50-00-0/Formaldehyde; 50-78-2/Aspirin; 64-17-5/Ethanol; 9000-70-8/Gelatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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