| Application of flow cytometry in pediatric hematology-oncology. | |
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MedLine Citation:
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PMID: 21462301 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Applications of flow cytometry in pediatric cancers have expanded substantially in recent years. In acute leukemias, the commonest childhood cancer, flow cytometry can now define complex antigenic profiles that are associated with specific cytogenetic/molecular defects and can also directly identify BCR-ABL fusion protein. Flow cytometry based scoring system has been described for diagnosis of myelodysplastic syndromes. In solid tumors, flow cytometry was previously used mainly to determine DNA content for prognosis; however, recent studies in children with neuroblastoma and Ewing sarcoma have identified its diagnostic utility. In this review, we will discuss the current and future applications of flow cytometry in pediatric hematology-oncology. Pediatr Blood Cancer © 2011 Wiley-Liss, Inc. |
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Authors:
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Neelam Varma; Shano Naseem |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-1 |
Journal Detail:
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Title: Pediatric blood & cancer Volume: - ISSN: 1545-5017 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101186624 Medline TA: Pediatr Blood Cancer Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
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Department of Hematology, Postgraduate Institute of Medical Education and Research, India. varmaneelam@yahoo.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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