Document Detail

Application of dual cyclodextrin systems in capillary electrophoresis enantioseparations.
MedLine Citation:
PMID:  23283785     Owner:  NLM     Status:  In-Data-Review    
The enantioseparation of acidic and neutral compounds can be successfully achieved in capillary electrophoresis (CE) using dual cyclodextrin (CD) systems. This chapter describes how to separate the enantiomers of acidic or neutral substances using dual CD systems made up of a negatively charged CD derivative, i.e., sulfobutyl-β-CD (SB-β-CD) or carboxymethyl-β-CD (CM-β-CD), in combination with a neutral one, namely, heptakis(2,3,6-tri-O-methyl)-β-CD (TM-β-CD). An acidic compound (carprofen) and a weakly acidic drug (pentobarbital) were selected as model compounds.
Anne-Catherine Servais; Marianne Fillet
Related Documents :
7467405 - Metabolism of clebopride in vitro. mass spectrometry and identification of products of ...
133645 - Analgesic and anti-inflammatory activity of 6-chloro-alpha-methyl-carbazole-2-acetic ac...
19503865 - Recognition of anti-mycolic acid antibody at self-assembled mycolic acid antigens on a ...
10405825 - Tannic acid and thiocarbohydrazide as structural reinforcement agents in the preparatio...
21154945 - Total synthesis of iso- and bongkrekic acids: natural antibiotics displaying potent ant...
20053485 - Synthesis of highly functionalized barbituric acids and study of their interactions wit...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  970     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2013  
Date Detail:
Created Date:  2013-01-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  289-95     Citation Subset:  IM    
Department of Pharmaceutical Sciences, University of Liège, Liège, Belgium,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Enantioseparations by capillary electrophoresis using cyclodextrins as chiral selectors.
Next Document:  Enantioseparations in nonaqueous capillary electrophoresis using charged cyclodextrins.