| Application of clinical indices of fetal growth and wellbeing to a novel laboratory species, the spiny mouse. | |
| | |
MedLine Citation:
|
PMID: 19092985 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Ultrasound was used to measure growth of the spiny mouse fetus throughout gestation and to record Doppler measurements of heart rate and umbilical blood flow to monitor fetal blood supply and wellbeing. Female spiny mice were anesthetized on 6 occasions throughout pregnancy. Ultrasound was performed with a Philips HDI 5000 machine using a compact linear CL15-7 transducer. Fetal heart rate and growth parameters increased across gestation. Blood flow through the umbilical artery and vein showed increasing velocity over gestation, and reduced resistance index. Blood flow through the ductus venosus also increased in velocity over gestation; however the resistance index remained constant. We have determined changes in umbilical blood flow throughout pregnancy in the spiny mouse, which resemble those seen in human pregnancy. We also confirm that ultrasound can be used as a valuable, non-invasive technique for measuring fetal growth and wellbeing in the spiny mouse. |
| | |
Authors:
|
Hayley Dickinson; Tania Griffiths; David W Walker; Graham Jenkin |
Related Documents
:
|
10687765 - Comparison of epidural and general anaesthesia for elective caesarean delivery accordin... 7600205 - The effects of fetal blood sampling on ductus venosus blood flow velocity waveforms. 17492825 - Application of high-intensity focused ultrasound for umbilical artery occlusion in a ra... 1542815 - The value of umbilical artery doppler analysis in the prediction of fetal acidosis in l... 8672175 - Simple versus sophisticated models of breath alcohol exhalation profiles. 17960565 - Flow-dependent regulation of angiopoietin-2. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Reproductive biology Volume: 8 ISSN: 1642-431X ISO Abbreviation: Reprod Biol Publication Date: 2008 Nov |
Date Detail:
|
Created Date: 2008-12-18 Completed Date: 2009-02-13 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101160559 Medline TA: Reprod Biol Country: Poland |
Other Details:
|
Languages: eng Pagination: 229-43 Citation Subset: IM |
Affiliation:
|
Monash University, Monash Medical Centre, Clayton 3178, VIC, Australia. Hayley.Dickinson@med.monash.edu.au |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Blood Flow Velocity / physiology Female Fetal Blood / physiology Fetal Development* Fetus / blood supply Heart Rate, Fetal Murinae / embryology* Pregnancy Ultrasonography, Prenatal Umbilical Arteries / ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Endometrial and myometrial secretion of androgens and estrone during early pregnancy and luteolysis ...
Next Document: The influence of tumor necrosis factor alpha (TNF) on the secretory function of bovine corpus luteum...