Document Detail

Application of the Starling resistor concept to the lungs during CPPV.
MedLine Citation:
PMID:  14809     Owner:  NLM     Status:  MEDLINE    
The application of the Starling resistor concept of the lungs during continuous positive pressure ventilation (CPPV) was evaluated. Ventilation and hemodynamics were studied in eight anesthetized and paralyzed dogs before and during the use of CPPV. CPPV resulted in an increase in transpulmonary pressure and functional residual capacity (FRC), and a decrease in arterial pH and mixed venous oxygen tension (PvO2). Cardica index decreased 32% (p less than 0.01) and stroke volume 51% (p less than 0.01). Neither right nor left transmural pressures changed but pulmonary vascular resistance increased 189% (p less than 0.01). This study supports the concept that the pulmonary vasculature behaves as a Starling resistor during the use of CPPV. The increase in pulmonary vascular resistance must be considered when transpulmonary pressure is raised by CPPV.
A M Katz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Critical care medicine     Volume:  5     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:    1977 Mar-Apr
Date Detail:
Created Date:  1977-05-25     Completed Date:  1977-05-25     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  67-72     Citation Subset:  IM    
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MeSH Terms
Blood Pressure
Cardiac Output
Heart Rate
Hydrogen-Ion Concentration
Lung / blood supply*
Oxygen / blood
Oxygen Consumption
Positive-Pressure Respiration*
Respiratory Function Tests
Vascular Resistance*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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