Document Detail


Application of Crystalline Cellulose Membrane (Veloderm®) on Split-Thickness Skin Graft Donor Sites in Burn or Reconstructive Plastic Surgery Patients.
MedLine Citation:
PMID:  23128129     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The present study was performed in China to compare the efficacy and safety of an advanced wound dressing made of crystalline cellulose (Veloderm) to a conventional treatment three of Vaseline gauze in the management of skin donor sites of burns or reconstructive plastic surgery. In this prospective, multicenter, open-labeled, randomized clinical trial performed in three Chinese burn centers in China, 96 patients who required autologous split skin graft were randomized into either the test (Veloderm) group or the control (Vaseline gauze) group. Average healing times in the test group and in the control group were 8.40 ± 2.90 and 8.92 ± 2.58 days, respectively, with median values of 7.00 and 8.00 days, respectively: the difference between two groups was statistically significant (P = .045). Scores for exudates, pain intensity, and peripheral erythema showed no difference between the groups; however, composite scores of three variables on day 10 postoperatively was significantly lower in the test group (0.00 ± 0.00 vs 0.13 ± 0.49; P = .043). The need for a dressing change was also significantly lower in the test group (12.5 vs 31.25%; P = .036). Veloderm is a safe and effective dressing that may offer some advantages over the traditional application of Vaseline gauze in the management of donor sites in burn or reconstructive plastic surgery patients.
Authors:
Jian Liu; Yeyang Li; Xinzhou Rong; Weihua Lin; Tao Zhang; Bingshun Wang; Xiaoyi Benjamin Li; Su Jiang; Qin Zhang
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-2
Journal Detail:
Title:  Journal of burn care & research : official publication of the American Burn Association     Volume:  -     ISSN:  1559-0488     ISO Abbreviation:  J Burn Care Res     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101262774     Medline TA:  J Burn Care Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
From the *Burn Center of Ruijin Hospital, Medicine School of Jiaotong University, Shanghai, China; †Department of Burn and Plastic, Guangzhou Red Cross Hospital, Guangzhou, China; ‡Department of Burn, Guangzhou First Municipal People's Hospital, Guangzhou, China; §Department of Biological Statistics, Medicine School of Jiaotong University, Shanghai, China; ║Lee's Pharmaceutical Holdings Limited, Shatin, Hong Kong SAR; and ¶Department of Clinical Research, Zhaoke Pharmaceutical (Hefei) Co. Ltd, Anhui, China.
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