Document Detail


Application of Campylobacter molecular classification and typing techniques in veterinary medicine: old-established methods and new perspectives.
MedLine Citation:
PMID:  17715819     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this review the application and usefulness of Campylobacter genotypical classification and typing in veterinary medicine will be discussed.While there is a large area of overlapping applications between the veterinary and the medical field, several differences exist, as the spectrum of veterinary pathogens is different from the human and contaminated food of healthy animal origin may cause disease in man. In general, genotyping in the veterinary field can be applied in three different areas: (a) purely diagnostic purposes for classification of Campylobacter species and subspecies, (b) typing methods useful for monitoring or surveillance of animals as well as food products of animal origin, and (c) typing methods that can be applied during outbreaks and for source tracing. In addition, typing methods applied in areas (b) and (c) should be distinguished in regard to local short-term and global long-term epidemiology, respectively. While a whole plethora of discriminative typing methods are available, classification tools of certain species and subspecies are still missing. Perspectively, as the genomes of many relevant Campylobacter species have now been sequenced, this will help to identify several species specific loci, the products of which should be available to develop easy and fast applicable diagnostic tools. Global cooperation, sharing of strains and databases should close the currently existing gaps in Campylobacter identification tools.
Authors:
Claudia Laturnus; Lothar H Wieler
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Berliner und Münchener tierärztliche Wochenschrift     Volume:  120     ISSN:  0005-9366     ISO Abbreviation:  Berl. Munch. Tierarztl. Wochenschr.     Publication Date:    2007 Jul-Aug
Date Detail:
Created Date:  2007-08-24     Completed Date:  2007-09-19     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0003163     Medline TA:  Berl Munch Tierarztl Wochenschr     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  267-78     Citation Subset:  IM    
Affiliation:
Institute for Microbiology and Epizootics, Freie Universität Berlin, Germany.
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MeSH Terms
Descriptor/Qualifier:
Animals
Bacterial Typing Techniques / methods*
Campylobacter / classification*,  genetics
Campylobacter Infections / microbiology,  veterinary
Disease Outbreaks
Food Contamination / analysis*
Food Microbiology
Genotype
Humans
Molecular Epidemiology*
Phylogeny*
Population Surveillance
Random Amplified Polymorphic DNA Technique / methods
Species Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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