| Applicability of common reference intervals for serum creatinine concentrations to the Croatian population. | |
| | |
MedLine Citation:
|
PMID: 19943808 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: In accordance with an ongoing activity for worldwide harmonization based on traceability in laboratory methods, the goal of this study was to validate the applicability of recommended "common" reference intervals for serum creatinine concentrations using a specific enzymatic method to the Croatian population. METHODS: The reference group consisted of 240 healthy subjects (120 males and 120 females), between 18 and 74 years of age (median 57 years), who were selected in accordance with the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) recommendations. Creatinine in serum was measured using the creatinine enzymatic assay (Olympus OSR61204) that was standardized to the isotopic dilution mass spectrometry (IDMS) method and National Institute of Standards and Technology (NIST) Standard Reference Material (SRM) 967. In addition, creatinine was measured using a kinetic Jaffe method (Olympus OSR6178) standardized to NIST SRM 909b level 2 standard. RESULTS: Method comparison between enzymatic creatinine (x) and the Jaffe kinetic method (y) gave the following P/B equation for the entire group (n=240): y=1.00x+17.00; r=0.968. Reference intervals for serum creatinine (central 95th percentiles) obtained using the enzymatic creatinine method ranged from 54 to 107 micromol/L for males and from 50 to 93 micromol/L for females. The IFCC recommended common reference intervals for global applications are 64-104 micromol/L and 49-90 micromol/L for males and females, respectively. CONCLUSIONS: Comparability of obtained results confirmed the applicability of recently recommended "common" reference intervals to the Croatian population for all laboratories measuring serum creatinine concentrations using enzymatic methods traceable to the IDMS method and NIST SRM 967. |
| | |
Authors:
|
Zlata Flegar-Mestri?; Sonja Perkov; Barbara Simonovi?; Dubravka Jureti? |
Related Documents
:
|
7460278 - Liquid-chromatographic determination of cimetidine, its known metabolites, and creatini... 7024328 - The specificity of the extraction fluorescence assay for serum or plasma quinidine. 22480438 - Resolution of volatile fuel compound profiles from ascocoryne sarcoides: a comparison b... 1601968 - Determination of apovincaminic acid in serum by means of high-performance liquid chroma... 12899998 - Simultaneous determination of naproxen and related compounds by hplc using porous graph... 16158298 - Comparison and evaluation of analysis procedures for the quantification of (2-methoxyet... |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Clinical chemistry and laboratory medicine : CCLM / FESCC Volume: 48 ISSN: 1434-6621 ISO Abbreviation: Clin. Chem. Lab. Med. Publication Date: 2010 Feb |
Date Detail:
|
Created Date: 2010-02-05 Completed Date: 2010-04-23 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9806306 Medline TA: Clin Chem Lab Med Country: Germany |
Other Details:
|
Languages: eng Pagination: 231-5 Citation Subset: IM |
Affiliation:
|
Institute of Clinical Chemistry Merkur University Hospital, Zagreb, Croatia. zlata.mestric@zg.t-com.hr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Creatinine / blood* Croatia Enzyme Assays / standards Female Humans Indicator Dilution Techniques / standards Isotopes Kinetics Laboratory Techniques and Procedures* / standards Male Mass Spectrometry / standards Middle Aged Reference Standards Reproducibility of Results Sensitivity and Specificity Young Adult |
| Chemical | |
Reg. No./Substance:
|
0/Isotopes; 60-27-5/Creatinine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Short Communication: The Beckman DxI 800 prolactin assay demonstrates superior specificity for monom...
Next Document: Laboratory reference intervals during pregnancy, delivery and the early postpartum period.