Document Detail

Apple (Malus domestica L. Borkh.) allergen Mal d 1: effect of cultivar, cultivation system, and storage conditions.
MedLine Citation:
PMID:  19845340     Owner:  NLM     Status:  MEDLINE    
It has been reported on the basis of skin prick tests and gene expression studies that apple cultivars differ in their allergenic potential. Only a few studies have tried to measure the amount of the major apple allergen Mal d 1 so far. Mal d 1 belongs to the pathogenesis-related proteins, a family of proteins that are induced by pathogens and environmental stress. Due to cross-reactivity between Bet v 1 and proteins present in several plant-derived foods, birch pollen allergic patients develop food allergies, most frequently to apples. Mal d 1 content was quantified in different apple cultivars, cultivated at the research stations Klein-Altendorf and Bavendorf, dependent on cultivation method and storage conditions by sandwich-ELISA. Apple cultivars differ considerably in their Mal d 1 content. A high variability in Mal d 1 content was determined within one cultivar and between the two locations for the same apple cultivar. In most cases organically cultivated fruit showed lower Mal d 1 content in comparison to fruit from integrated production. At harvest the detected concentration of Mal d 1 was low, but during storage the Mal d 1 content increased significantly.
Anne Matthes; Michaela Schmitz-Eiberger
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  57     ISSN:  1520-5118     ISO Abbreviation:  J. Agric. Food Chem.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-11-20     Completed Date:  2010-02-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  10548-53     Citation Subset:  IM    
Institute of Crop Science and Resource Conservation, Horticultural Science, University of Bonn, Auf dem Huegel 6, D-53121 Bonn, Germany.
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MeSH Terms
Agriculture / methods
Allergens / analysis*
Enzyme-Linked Immunosorbent Assay
Food Preservation / methods*
Fruit / growth & development*,  immunology*
Health Food / analysis
Malus / growth & development*,  immunology*
Plant Proteins / analysis*
Reproducibility of Results
Species Specificity
Reg. No./Substance:
0/Allergens; 0/MALD1 protein, Malus domestica; 0/Plant Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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