Document Detail

Appetite stimulants use in cystic fibrosis.
MedLine Citation:
PMID:  18219690     Owner:  NLM     Status:  MEDLINE    
Cystic fibrosis (CF) is an autosomal recessive disease. It affects multiple body organs. The lungs and pancreas are the most affected which results in progressive lung damage and pancreatic insufficiency. Due to the disease process, CF patients require significantly higher caloric intake than recommended for other individuals. The nutritional goal for CF patients is to achieve normal growth and development and, once genetic potential is reached, to maintain good nutritional status throughout life. Evidence has shown that lung function is closely associated with nutritional status in CF and that nutritional status is an independent predictor of survival. Most CF patients are on a high calorie diet to help achieve normal growth and development and maintain good lung function. Inadequate caloric intake in CF can lead to malnutrition. Malnutrition in CF requires careful, multidisciplinary history taking, physical exam, and overall patient/family assessment. Only by determining the actual cause of the malnutrition can appropriate and safe therapies be used to treat it. Appetite stimulants, although efficacious in treating malnutrition in CF, should only be prescribed if decreased food intake secondary to inadequate appetite is the principal cause of the malnutrition and all other contributing factors have been assessed, ruled-out or treated. In this review, we attempted to summarize the use of several appetite stimulants used in CF and other diseases to improve appetite and maximize caloric intake.
Samya Z Nasr; Donna Drury
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pediatric pulmonology     Volume:  43     ISSN:  1099-0496     ISO Abbreviation:  Pediatr. Pulmonol.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-04     Completed Date:  2008-04-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8510590     Medline TA:  Pediatr Pulmonol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  209-19     Citation Subset:  IM    
Copyright Information:
(c) 2008 Wiley-Liss, Inc.
Pediatric Pulmonology, University of Michigan Health System, Ann Arbor, Michigan 48109-5212, USA.
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MeSH Terms
Antidepressive Agents / therapeutic use
Antipsychotic Agents / therapeutic use
Appetite Stimulants / therapeutic use*
Child Nutrition Disorders / complications,  etiology,  prevention & control*
Child, Preschool
Cystic Fibrosis / complications*
Human Development
Human Growth Hormone / therapeutic use
Nutrition Assessment
Reg. No./Substance:
0/Antidepressive Agents; 0/Antipsychotic Agents; 0/Appetite Stimulants; 12629-01-5/Human Growth Hormone

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