Document Detail

Appendectomy and the risk of tubal infertility.
MedLine Citation:
PMID:  3785307     Owner:  NLM     Status:  MEDLINE    
We studied the importance of a history of appendectomy for appendicitis in 279 women with laparoscopically or surgically diagnosed tubal infertility and a control group of 957 fertile women. After controlling for the effects of age, use of an intrauterine device for contraception, a history of pelvic inflammatory disease, and other potential confounding variables, we found that no excess risk of tubal infertility was associated with a simple appendectomy without rupture. However, when the operation was reportedly for a ruptured appendix, the relative risk of tubal infertility was 4.8 (95 percent confidence interval, 1.5 to 14.9) for women who had never been pregnant and 3.2 (95 percent confidence interval, 1.1 to 9.6) for women with one or more previous pregnancies. We conclude that the early diagnosis and treatment of suspected appendicitis in girls and women of reproductive age may reduce the incidence of tubal infertility resulting from the sequelae of a ruptured appendix.
B A Mueller; J R Daling; D E Moore; N S Weiss; L R Spadoni; B V Stadel; M R Soules
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The New England journal of medicine     Volume:  315     ISSN:  0028-4793     ISO Abbreviation:  N. Engl. J. Med.     Publication Date:  1986 Dec 
Date Detail:
Created Date:  1986-12-30     Completed Date:  1986-12-30     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1506-8     Citation Subset:  AIM; IM    
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MeSH Terms
Appendicitis / surgery
Fallopian Tube Diseases / etiology*
Infertility, Female / etiology*
Intestinal Perforation / complications
Intrauterine Devices
Pelvic Inflammatory Disease / complications
Postoperative Complications*
Rupture, Spontaneous
Grant Support
1 NO1 HD 02821/HD/NICHD NIH HHS; 1 R23 HD 215 28 01/HD/NICHD NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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