Document Detail


Apparent life-threatening events: Assessment, Risks, Reality.
MedLine Citation:
PMID:  21458741     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Apparent life-threatening events (ALTEs), because of their prevalence as well as their potential to hide serious diseases and consume significant medical resources, remain a challenge for physicians caring for infants. In this review, we focused on the assessment of the well-appearing infant for the most serious diagnoses, namely serious bacterial infections, seizure disorders, child abuse, metabolic disorders and severe apnoea with hypoxemia. Our extensive review of the literature has highlighted the difficulties physicians are facing in this evaluation, especially for the youngest infants (aged less than 2 months). Large-scale prospective studies are needed to identify risk factors and to guide physicians as to who should be investigated and the minimal investigation needed to avoid missing such conditions as serious bacterial infection, abusive head injury or repeated severe cardiorespiratory events. While infants with severe forms of metabolic disorders typically present with evident signs and symptoms, less severe forms of metabolic disorders, seizure disorders, and some forms of child abuse will often be diagnosed only when recurrent events are investigated.
Authors:
Naif Al Khushi; Aurore Côté
Publication Detail:
Type:  Journal Article     Date:  2010-11-26
Journal Detail:
Title:  Paediatric respiratory reviews     Volume:  12     ISSN:  1526-0550     ISO Abbreviation:  Paediatr Respir Rev     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2011-04-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100898941     Medline TA:  Paediatr Respir Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  124-32     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Pediatrics and Respiratory Medicine Division, The Montreal Children's Hospital, McGill University Health Centre, Montreal Canada.
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