Document Detail

Apparent life threatening event and gastric antral ulcer in a full-term infant: any possible relationship?
MedLine Citation:
PMID:  21305880     Owner:  NLM     Status:  In-Process    
We describe the case of an apparently healthy newborn infant who in 7th day of life showed an episode of haematemesis and in 13th day of life presented an episode of apparent life threatening event (ALTE). A fibroscopy of the upper digestive tract showed a great ulcer of the gastric antrum and esophagitis limited to the mucosa. Gastrinemia in the blood showed high values (121 pg/ml). The relationship between ALTE and gastric ulcer may be casual, however in literature a gastroenteric cause is present in about 50% of ALTE in which an etiologic cause is found. We speculate that in the present case the increase of gastrin secretion reduced gastric pH which facilitated the onset of gastric ulcer and esophagitis with ALTE due to pain or reflex.
Pier Luigi Bacchini; Enzo Romanini; Cinzia Magnani; Gian Luigi De'Angelis; Giulio Bevilacqua
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta bio-medica : Atenei Parmensis     Volume:  81     ISSN:  0392-4203     ISO Abbreviation:  Acta Biomed     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2011-02-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101295064     Medline TA:  Acta Biomed     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  144-6     Citation Subset:  IM    
Department of Gynecology, Obstetrics and Neonatological Sciences, University Hospital, Parma, Italy.
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