Document Detail

Apparent in vivo retroconversion of dietary arachidonic to linoleic acid in essential fatty acid-deficient rats.
MedLine Citation:
PMID:  3092868     Owner:  NLM     Status:  MEDLINE    
Essential fatty acid-deficient rats were fed ethyl [U-14C]arachidonate (308 dpm/nmol) and when a decrease in the transepidermal water loss was seen, the epidermal sphingolipids, acylglucosylceramide and acylceramide were isolated. [14C]Linoleic acid (approx. 130 dpm/nmol) was present in both lipid classes, while the substrate was only detected in the former. These results intimate that in vivo retroconversion of arachidonic to linoleic acid can be induced in the rat.
H S Hansen; B Jensen; P von Wettstein-Knowles
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biochimica et biophysica acta     Volume:  878     ISSN:  0006-3002     ISO Abbreviation:  Biochim. Biophys. Acta     Publication Date:  1986 Sep 
Date Detail:
Created Date:  1986-10-30     Completed Date:  1986-10-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0217513     Medline TA:  Biochim Biophys Acta     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  284-7     Citation Subset:  IM    
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MeSH Terms
Arachidonic Acid
Arachidonic Acids / metabolism*
Carbon Radioisotopes / diagnostic use
Fatty Acids, Essential / deficiency*
Linoleic Acid
Linoleic Acids / metabolism*
Skin / metabolism
Sphingolipids / metabolism
Reg. No./Substance:
0/Arachidonic Acids; 0/Carbon Radioisotopes; 0/Fatty Acids, Essential; 0/Linoleic Acids; 0/Sphingolipids; 2197-37-7/Linoleic Acid; 506-32-1/Arachidonic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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