Document Detail


Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes.
MedLine Citation:
PMID:  6090933     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The repeated mini-exon sequence that encodes the first 35 base pairs of all variant surface antigen mRNAs of Trypanosoma brucei directs the synthesis of a discrete 137-nucleotide transcript. It thus seems that variant surface antigen mRNAs are transcribed discontinuously, and we present two alternative models for how this might occur.
Authors:
D A Campbell; D A Thornton; J C Boothroyd
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nature     Volume:  311     ISSN:  0028-0836     ISO Abbreviation:  Nature     Publication Date:    1984 Sep 27-Oct 3
Date Detail:
Created Date:  1984-11-06     Completed Date:  1984-11-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0410462     Medline TA:  Nature     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  350-5     Citation Subset:  IM    
Data Bank Information
Bank Name/Acc. No.:
GENBANK/X00935
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MeSH Terms
Descriptor/Qualifier:
Animals
Base Sequence
Cloning, Molecular
DNA Restriction Enzymes
Genes*
Glycoproteins / genetics*
Models, Genetic
Transcription, Genetic*
Trypanosoma brucei brucei / genetics*
Variant Surface Glycoproteins, Trypanosoma
Chemical
Reg. No./Substance:
0/Glycoproteins; 0/Variant Surface Glycoproteins, Trypanosoma; EC 3.1.21.-/DNA Restriction Enzymes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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