| Apoptotic and survival signaling mediated through death receptor members during metamorphosis in the African clawed frog Xenopus laevis. | |
| | |
MedLine Citation:
|
PMID: 22245291 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The tumor necrosis factor (TNF) superfamily includes death receptor (DR) ligands, such as TNF-α, FasL, and TRAIL. Death receptors (DRs) induce intracellular signaling upon engagement of their cognate DR ligands, either leading to apoptosis, survival, or proinflammatory responses. The DR signaling is mediated by the recruitment of several death domain (DD)-containing molecules such as Fas-associated death domain (FADD) and receptor-interacting protein (RIP) 1. In this review, we describe DR signaling in mammals, and describe recent findings of DR signaling during metamorphosis in the African clawed frog Xenopus laevis. Specifically, we focus on the cell fate (apoptosis or survival) mediated through a DR ligand, TNF-α or TRAIL in endothelial cells or red blood cells (RBCs). In addition, we discuss relationships between thyroid hormone-induced metamorphosis and DR signaling. |
| | |
Authors:
|
Michihiko Ito; Kei Tamura; Shuuji Mawaribuchi; Nobuhiko Takamatsu |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-8 |
Journal Detail:
|
Title: General and comparative endocrinology Volume: - ISSN: 1095-6840 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-16 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0370735 Medline TA: Gen Comp Endocrinol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Bioscience, School of Science, Kitasato University, 1-15-1 Kitasato, Sagamihara 228-8555, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Defining the contribution of select neuropeptides and their receptors in regulating sesquiterpenoid ...
Next Document: Pure Mini-laparoscopic Transperitoneal Pyeloplasty in an Adult Population: Feasibility, Safety, and ...