| Apoptotic pathways: involvement of lysosomal proteases. | |
| | |
MedLine Citation:
|
PMID: 12437086 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Apoptosis or programmed cell death is the major mechanism used by multicellular organisms to remove infected, excessive and potentially dangerous cells. Cysteine proteases from the caspase family play a crucial role in the process. However, there is increasing evidence that lysosomal proteases are also involved in apoptosis. In this review various lysosomal proteases and their potential contribution to propagation of apoptosis are discussed. |
| | |
Authors:
|
Boris Turk; Veronica Stoka; Jerica Rozman-Pungercar; Tina Cirman; Gabriela Droga-Mazovec; Kristina Oresić; Vito Turk |
Related Documents
:
|
12860476 - Effect of fraxetin and myricetin on rotenone-induced cytotoxicity in sh-sy5y cells: com... 16309216 - Caspase-3 activation and induction of parp cleavage by cyclic dipeptide cyclo(phe-pro) ... 20011976 - Potentiation of (-)-epigallocatechin-3-gallate-induced apoptosis by bortezomib in multi... 9264376 - Camptothecin-induced apoptosis in p53-null human leukemia hl60 cells and their isolated... 16148026 - Regulation of rho signaling pathways in interleukin-2-stimulated human t-lymphocytes. 16701146 - Targeting dendritic cells in allergen immunotherapy. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: Biological chemistry Volume: 383 ISSN: 1431-6730 ISO Abbreviation: Biol. Chem. Publication Date: 2002 Jul-Aug |
Date Detail:
|
Created Date: 2002-11-19 Completed Date: 2003-07-14 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9700112 Medline TA: Biol Chem Country: Germany |
Other Details:
|
Languages: eng Pagination: 1035-44 Citation Subset: IM |
Affiliation:
|
Department of Biochemistry and Molecular Biology, Jozef Stefan Institute, Ljubljana, Slovenia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Apoptosis* Endopeptidases / physiology* Humans Proteins / physiology* Signal Transduction Tumor Necrosis Factor-alpha / metabolism |
| Chemical | |
Reg. No./Substance:
|
0/Proteins; 0/Tumor Necrosis Factor-alpha; 0/lysosomal proteins; EC 3.4.-/Endopeptidases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Expression and inheritance of nine transgenes in rice.
Next Document: Human tissue kallikreins: a new enzymatic cascade pathway?