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Apoptosis-inducing antifungal peptides and proteins.
MedLine Citation:
PMID:  21936846     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Despite the availability of various classes of antimycotics, the treatment of patients with systemic fungal infections is challenging. Therefore the development of new antifungals is urgently required. Promising new antifungal candidates are antimicrobial peptides. In the present review, we provide an overview of antifungal peptides isolated from plants, insects, amphibians and mammals that induce apoptosis. Their antifungal spectrum, mode of action and toxicity are discussed in more detail.
Authors:
Katrijn De Brucker; Bruno P A Cammue; Karin Thevissen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biochemical Society transactions     Volume:  39     ISSN:  1470-8752     ISO Abbreviation:  Biochem. Soc. Trans.     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-09-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7506897     Medline TA:  Biochem Soc Trans     Country:  England    
Other Details:
Languages:  eng     Pagination:  1527-32     Citation Subset:  IM    
Affiliation:
CMPG (Centre of Microbial and Plant Genetics), Katholieke Universiteit Leuven, Kasteelpark Arenberg 20, 3001 Heverlee, Belgium.
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