Document Detail


Apoplexy of a microprolactinoma during pregnancy: A case report and review of the literature.
MedLine Citation:
PMID:  22982795     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Objective To report a rare case of apoplexy in a microprolactinoma during pregnancy.Methods We present the clinical presentation, laboratory, radiologic findings and management in a patient that presented with pituitary apoplexy during early pregnancy. We review the pertinent literature and management options.Results A 37-year-old woman with a history of a microprolactinoma presented at the 16th week of her first pregnancy with a sudden onset of severe headache, nausea, vomiting and blurred vision. MRI showed a sellar heterogeneous mass with suprasellar extension and contact with the optic chiasm compatible with adenoma apoplexy. The patient's visual fields were normal. Conservative management was followed by rapid clinical improvement and a marked regression of the sellar mass after five weeks of cabergoline therapy. Uneventful pregnancy resulted in the delivery of an alive and healthy baby. A repeat MRI was performed one week after delivery and showed resolution of the microadenoma. Three months postpartum, the patient recovered regular menses and had sustained normal prolactin levels without treatment.Conclusion This case illustrates a rare occurrence of apoplexy in a microprolactinoma during pregnancy which was managed conservatively and led to a complete regression of the pituitary tumor.
Authors:
Nathalie Couture; Nahla Aris-Jilwan; Omar Serri
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-14
Journal Detail:
Title:  Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists     Volume:  -     ISSN:  1934-2403     ISO Abbreviation:  Endocr Pract     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9607439     Medline TA:  Endocr Pract     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-11     Citation Subset:  -    
Affiliation:
Division of Endocrinology, Department of Medicine, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
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