Document Detail


Aplasia cutis congenita in surviving co-twins: four unrelated cases.
MedLine Citation:
PMID:  11841641     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Four unrelated patients born from twin pregnancies and showing extracranial aplasia cutis congenita are reported. All the patients lost their co-twins during the first half of the pregnancy. Two of the patients had the characteristic truncal and symmetrical type of aplasia cutis associated with fetus papyraceus and placental abnormalities. The presence of multiple hepatic hematomas in one of them gives further credit to a "vascular disruption" as the possible pathogenetic mechanism of the disorder. The two other patients were born with symmetrical aplasia cutis at the extensory aspects of both knees, which presumably represents a milder expression of the former defect. Thus the so-called aplasia cutis with fetus papyraceus shows heterogeneity in localization, extension, presence of extracutaneous abnormalities, and possible association with fetus papyraceus at birth. To include all the patients affected by this peculiar type of aplasia cutis congenita, the designation of aplasia cutis with extracranial symmetrical involvement is proposed.
Authors:
S Cambiaghi; A Schiera; L Tasin; C Gelmetti
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric dermatology     Volume:  18     ISSN:  0736-8046     ISO Abbreviation:  Pediatr Dermatol     Publication Date:    2001 Nov-Dec
Date Detail:
Created Date:  2002-02-13     Completed Date:  2002-03-13     Revised Date:  2009-03-03    
Medline Journal Info:
Nlm Unique ID:  8406799     Medline TA:  Pediatr Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  511-5     Citation Subset:  IM    
Affiliation:
Istituto di Scienze Dermatologiche, IRCCS Policlinico e Università di Milano, Milan, Italy. stefanodoc@tiscalinet.it
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MeSH Terms
Descriptor/Qualifier:
Diseases in Twins*
Ectodermal Dysplasia / genetics*,  pathology
Female
Fetal Death / pathology
Fetal Diseases / pathology
Humans
Infant
Infant, Newborn
Male
Pregnancy
Pregnancy, Multiple
Skin Diseases / pathology
Twins, Monozygotic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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