Document Detail


Aphthous ulcerations associated with trisomy 8-positive myelodysplastic syndrome.
MedLine Citation:
PMID:  17637369     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The association of Behçet's disease with myelodysplastic syndromes has been established in the hematologic, gastrointestinal, and medical genetics literature; trisomy 8 is a feature present in 70% of these reports. Because trisomy 8 is ordinarily present in only 14% of patients with myelodysplastic syndrome, this is a significant overrepresentation. We describe a patient with recurrent aphthous stomatitis who was subsequently diagnosed with trisomy 8-positive myelodysplastic syndrome after an unexplained macrocytosis was further investigated.
Authors:
Lauren A Fine; Laura D Hoffman; Mark D Hoffman
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  57     ISSN:  1097-6787     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-07-19     Completed Date:  2007-08-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S38-41     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Rush University, Chicago, Illinois, IL 60612, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Chromosomes, Human, Pair 8*
Female
Humans
Myelodysplastic Syndromes / complications,  genetics*
Recurrence
Stomatitis, Aphthous / etiology*
Trisomy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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