Document Detail

Apheresis as rescue therapy in a severe case of sudden hearing loss.
MedLine Citation:
PMID:  21786250     Owner:  NLM     Status:  Publisher    
A 23-year-old man complained of progressive left ear hearing loss and tinnitus and was unsuccessfully treated with steroids and mannitol. Four months later he presented with sudden, severe, asymmetrical, bilateral sensorineural hearing loss. The results of the laboratory workup were normal except for antinuclear autoantibodies. Auditory brain stem responses showed absent peak and interpeak latencies on both sides. The combination of plasma exchange with high doses of steroids resulted in a definite improvement. Plasmapheresis combined with steroid administration can be used as second-line therapy in idiopathic, sudden sensorineural hearing loss.
Mirella Alpa; Sebastiano Bucolo; Fabio Beatrice; Osvaldo Giachino; Dario Roccatello
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-22
Journal Detail:
Title:  The International journal of artificial organs     Volume:  -     ISSN:  1724-6040     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802649     Medline TA:  Int J Artif Organs     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Center of Research on Immunopathology and Documentation of Rare Diseases (CMID), G. Bosco Hospital, Turin - Italy and Master's Program (Level II) in Rare Diseases, University of Turin, Turin - Italy.
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