Document Detail


Aphasia following striatocapsular infarction may be explained by concomitant small cortical infarct on diffusion-weighted imaging.
MedLine Citation:
PMID:  15703465     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The underlying mechanism of aphasia following striatocapsular infarction (SCI) remains controversial. We hypothesized that aphasia resulting from SCI might be associated with concomitant cortical lesions, which can be demonstrated by diffusion-weighted imaging (DWI). METHODS: We analyzed 24 patients with left SCI who underwent DWI and MR angiography within 2 days after the onset. Aphasia was assessed by the modified Korean version of the Boston Diagnostic Aphasia Examination test. RESULTS: DWI showed the presence of additional ischemic lesions involving the cortical areas in 13 of 24 SCI patients (54%). Ten patients (42%) showed aphasia. All 10 patients with aphasia had cortical lesions in addition to SCI (p = 0.0002), whereas 21% (3/14) of the nonaphasic patients had additional cortical lesions. Conventional MRI did not reveal the presence of corresponding acute cortical lesions in any of the aphasic patients. There was no difference between the patients with and without aphasia in terms of their stroke etiology. CONCLUSIONS: Our data suggest that aphasia due to SCI in the acute stage may be attributed to direct cortical injury, whose presence can be demonstrated by DWI, even though it might be invisible on conventional imaging.
Authors:
Moon-Ku Han; Dong-Wha Kang; Sang-Wuk Jeong; Jae-Kyu Roh
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Publication Detail:
Type:  Journal Article     Date:  2005-02-08
Journal Detail:
Title:  Cerebrovascular diseases (Basel, Switzerland)     Volume:  19     ISSN:  1015-9770     ISO Abbreviation:  Cerebrovasc. Dis.     Publication Date:  2005  
Date Detail:
Created Date:  2005-04-08     Completed Date:  2005-06-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9100851     Medline TA:  Cerebrovasc Dis     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  220-4     Citation Subset:  IM    
Copyright Information:
Copyright 2005 S. Karger AG, Basel.
Affiliation:
Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea. rohjk@snu.ac.kr
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MeSH Terms
Descriptor/Qualifier:
Aged
Aphasia / etiology,  pathology*
Cerebral Angiography
Cerebral Cortex / pathology
Cerebral Infarction / complications,  pathology*
Corpus Striatum / pathology
Diffusion Magnetic Resonance Imaging*
Female
Humans
Internal Capsule / pathology
Male
Middle Aged
Telencephalon / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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