Document Detail


Aphasia: an early uncommon complication of ovarian stimulation without ovarian hyperstimulation syndrome.
MedLine Citation:
PMID:  17207328     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thromboembolic disease associated with assisted reproductive techniques is extremely rare. A 21-year-old woman with primary infertility underwent an ovulation induction cycle with luteal long protocol. Twenty-four hours following oocyte retrieval, the patient complained of difficulty in speaking. On neurological examination, mild disorientation, motor aphasia, and right-sided hypoesthesia were noted. Brain computed tomography scanning without contrast revealed left parietal lob infarct. Brain magnetic resonance imaging (MRI), MRI angiography (MRA) and perfusion MRI demonstrated an occlusion of the posterior division of the left middle cerebral artery (MCA). Physical, ultrasound examinations and laboratory test evaluation failed to reveal ovarian hyperstimulation syndrome. Except for ovarian stimulation, no additional risk factors for stroke were shown. Following anticoagulation and speech therapy, the patient recovered completely within eight months. One year after the left MCA thrombosis, she conceived spontaneously and had an uncomplicated vaginal delivery of a live male infant weighing 2900 g at 38 weeks gestation. This case supports that ovulation induction and assisted reproductive techniques may be a newly recognized cause of cerebral infarction in otherwise healthy women.
Authors:
Aygul Demirol; Suleyman Guven; Timur Gurgan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  14     ISSN:  1472-6483     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-08     Completed Date:  2007-02-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  England    
Other Details:
Languages:  eng     Pagination:  29-31     Citation Subset:  IM    
Affiliation:
CLINIC Women Health, Infertility and IVF Centre, Ankara, Turkey. ademirol@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Aphasia / etiology*
Female
Humans
Infarction, Middle Cerebral Artery / diagnosis,  etiology
Magnetic Resonance Angiography
Ovarian Hyperstimulation Syndrome / diagnosis
Ovulation Induction / adverse effects*
Parietal Lobe / pathology
Risk Factors
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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