Document Detail

Aortocoronary vein graft flow in response to peripheral venous administration of sodium nitroprusside or diazepam.
MedLine Citation:
PMID:  879884     Owner:  NLM     Status:  MEDLINE    
Vein graft flow (VGF) in response to peripheral venous administration of sodium nitroprusside (SNP) or diazepam was studied in 13 anesthetized patients following cardiopulmonary bypass for aortocoronary vein bypass graft operations. SNP (0.5 microgram/kg/min) significantly reduced mean arterial pressure (p less than 0.05). VGF paralleled the decreased blood pressure, but the reduction was not significant (p greater than 0.05). Diazepam (0.1 mg/kg) did not significantly alter blood pressure or VGF. We conclude that peripheral venous administration of SNP or diazepam is not a pharmacologically reliable method by which to increase VGF in the period immediately following a graft operation.
R K Stoelting; R D King
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  24     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1977 Jul 
Date Detail:
Created Date:  1977-08-12     Completed Date:  1977-08-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  59-61     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Pressure / drug effects
Cardiopulmonary Bypass*
Coronary Circulation / drug effects*
Diazepam / pharmacology*
Ferricyanides / pharmacology*
Nitroprusside / pharmacology*
Papaverine / pharmacology
Transplantation, Autologous
Veins / transplantation*
Reg. No./Substance:
0/Ferricyanides; 15078-28-1/Nitroprusside; 439-14-5/Diazepam; 58-74-2/Papaverine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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