Document Detail

Aortitis and aortic occlusion in Crohn's disease.
MedLine Citation:
PMID:  25463334     Owner:  NLM     Status:  Publisher    
Patients with Crohn's disease (CD) or ulcerative colitis (UC) are known to be at increased risk of arterial thromboembolic complications. We report the case of a 33 year-old woman suffering from Crohn's disease for 19 years who presented lower limb claudication. CT-scan revealed an aorto-iliac occlusion extending from the level of the inferior mesenteric artery to both iliac bifurcations. Endovascular recanalization was attempted as a first option but failed. We then performed an aortobifemoral bypass through a left retroperitoneal approach that allowed a total relief of the symptoms. Histological study of the aorta demonstrated a non-specific aortitis with lympho-histiocytic cells infiltration in the media and adventitia tunica. There was no signs of associated vasculitis. At the light of a literature review, we discussed our surgical strategy and the inflammation of the aortic wall as local factor of thrombosis, that has never been previously described.
Charline Delay; Adeline Schwein; Anne Lejay; Sébastien Gaertner; Boris Aleil; Fabien Thaveau; Yannick Georg; Nabil Chakfe
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-11-22
Journal Detail:
Title:  Annals of vascular surgery     Volume:  -     ISSN:  1615-5947     ISO Abbreviation:  Ann Vasc Surg     Publication Date:  2014 Nov 
Date Detail:
Created Date:  2014-12-2     Completed Date:  -     Revised Date:  2014-12-3    
Medline Journal Info:
Nlm Unique ID:  8703941     Medline TA:  Ann Vasc Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
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