Document Detail

Aortic wall alterations after use of gelatin-resorcinol-formalin glue.
MedLine Citation:
PMID:  11845891     Owner:  NLM     Status:  MEDLINE    
We report the case of a patient who underwent reoperation 8 years after aortic valve replacement because of aneurysmal dilatation of the aortic root. During the initial intervention, gelatin-resorcinol-formalin glue had been applied on the outside of the aortic root. Perioperative examination revealed a necrotic appearance of the right coronary sinus, with contained ruptures at two different sites. Histologic analysis showed major destruction of the aortic root media, leading to vascular wall thinning and rupture. The use of gelatin-resorcinolformalin glue may expose patients to major alterations of the aortic wall.
Matthias Kirsch; Maryvonne Ginat; Laure Lecerf; Rémi Houël; Daniel Loisance
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  73     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-02-15     Completed Date:  2002-03-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  642-4     Citation Subset:  AIM; IM    
Department of Cardiothoracic Surgery, Association Claude Bernard, Hĵpital Henri Mondor, Créteil, France.
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MeSH Terms
Aorta, Thoracic / drug effects*,  pathology,  surgery
Aortic Aneurysm, Thoracic / chemically induced*,  pathology,  surgery
Aortic Valve Insufficiency / surgery*
Blood Vessel Prosthesis Implantation
Drug Combinations
Formaldehyde / administration & dosage,  adverse effects*
Gelatin / administration & dosage,  adverse effects*
Heart Valve Prosthesis Implantation*
Middle Aged
Resorcinols / administration & dosage,  adverse effects*
Rupture, Spontaneous
Sinus of Valsalva / drug effects*,  pathology
Tunica Media / drug effects,  pathology
Reg. No./Substance:
0/Drug Combinations; 0/Resorcinols; 0/gelatin-resorcinol-formaldehyde tissue adhesive; 50-00-0/Formaldehyde; 9000-70-8/Gelatin
Comment In:
Ann Thorac Surg. 2003 Mar;75(3):1063   [PMID:  12645754 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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