| Aortic valvuloplasty in the fetus: technical characteristics of successful balloon dilation. | |
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MedLine Citation:
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PMID: 16227042 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To describe technical aspects of successful fetal aortic valvuloplasty, with particular attention to balloon size. STUDY DESIGN: We retrospectively reviewed all procedural records and echocardiograms pertaining to 26 attempts at fetal aortic valve dilation performed at a single center over a period of 4 years. We assessed the effect of valvuloplasty as determined by echocardiographic appearance at the time of intervention and in follow-up. RESULTS: In 20 of 26 fetuses who had technically successful aortic valve dilation (median balloon:annulus ratio=1.1), all had improved antegrade flow and 12 had at least mild regurgitation after dilation. Use of an oversized balloon was associated with the onset of moderate or severe aortic regurgitation, seen in 5 fetuses. This aortic regurgitation was well tolerated and improved through the remainder of gestation. CONCLUSIONS: These data imply that fetal aortic valves can be dilated safely with larger balloons than are commonly used for postnatal dilation. The observation of spontaneous improvement in postdilation aortic regurgitation further suggests that fetal valve tissue behaves uniquely. |
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Authors:
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Audrey C Marshall; Wayne Tworetzky; Lisa Bergersen; Doff B McElhinney; Carol B Benson; Russell W Jennings; Louise E Wilkins-Haug; Gerald R Marx; James E Lock |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of pediatrics Volume: 147 ISSN: 0022-3476 ISO Abbreviation: J. Pediatr. Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2005-10-17 Completed Date: 2005-12-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: United States |
Other Details:
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Languages: eng Pagination: 535-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiology and Department of Surgery, Children's Hospital Boston, Boston, Massachusetts 02115, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aortic Valve Insufficiency
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etiology Aortic Valve Stenosis / therapy*, ultrasonography Balloon Dilatation / adverse effects, instrumentation, methods* Fetal Diseases / therapy* Fetal Heart / ultrasonography Fetal Therapies / instrumentation, methods Humans Retrospective Studies Treatment Outcome |
| Comments/Corrections | |
Comment In:
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J Pediatr. 2005 Oct;147(4):424-6
[PMID:
16227023
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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